malaria immunity. what’s your superpower?

Meme insisted that I got tested at the clinic.

I carry sickle cell trait.

Let’s clear a few things up before I go any further.

Sickle Cell Disease (SCD) also known as Sickle Cell Anemia is an inherited form of anemia in which mutated (sickle-shaped) red blood cells do not carry enough oxygen throughout the body. Because of this, the red blood cells “stick to the walls” and cannot pass through capillaries. As a result, this causes chronic pain (sickle cell crisis) typically at the location of the “sticking,” which is often crippling for those who suffer from SCD. SCD is common in those of African descent, but similarly Mediterranean, Middle Eastern, Caribbean, and Asian Indian ancestry can also have SCD.

A carrier of Sickle Cell Trait is a person who only inherited one mutated gene of SCD. Remember dominant and recessive genes in biology class? In most cases, carriers of  sickle cell trait are asymptomatic and commonly do not have issues related to SCD, although there are always exceptions.

Interesting research shows that carriers of the sickle cell trait are IMMUNE to malaria, because SCD stems from mutated red blood cells which carried malaria.

Now, malaria is a real nasty disease. Malaria is caused when an infected mosquito transmits a parasite, most commonly P. falciparum, to its host. Symptoms of malaria include fever, headache, chills, and vomiting.  If left untreated, malaria can lead to more severe symptoms including death.

Does anyone like needles? Nurse Anna laughing at pain.

Don’t get me wrong. Being genetically resistant to malaria is really cool. But, it does not make me immune to mosquito bites or mosquitoes buzzing in my ears a night. So, I make sure to sleep under my properly installed ITN (insecticide-treated net) and wear insect repellent.

Doctors still recommend carriers who live in malaria zones to take daily prophylaxis, especially during the rainy season – which is now in Namibia.

Hey, the more you know.

❤ Krystal